THR Simulator – the software for generating radiographs of THR prosthesis

THR Simulator – the software for generating radiographs of THR prosthesis

BACKGROUND Measuring the orientation of acetabular cup after total hip arthroplasty is important for prognosis. The verification of these measurement methods will be easier and more feasible if we can synthesize prosthesis radiographs in each simulated condition. One reported method used an expensive mechanical device with an indeterminable precision. We thus develop a program, THR Simulator, t...

Author's response to reviews Title: THR Simulator - The Software for Generating Radiographs of THR Prosthesis Authors:

Total hip replacement (THR).

The authors present history, indications and complications of total hip replacement in 206 patients in a period of 10 months. They compare the rate of complications with published data. They present pre-operative examination, prophylaxis and specific problems in their conditions.

Influence of prosthesis design and implantation technique on implant stresses after cementless revision THR

BACKGROUND Femoral offset influences the forces at the hip and the implant stresses after revision THR. For extended bone defects, these forces may cause considerable bending moments within the implant, possibly leading to implant failure. This study investigates the influences of femoral anteversion and offset on stresses in the Wagner SL revision stem implant under varying extents of bone def...

Ser/Thr Phosphatases: The New Frontier for Myeloid Leukemia Therapy?

Myeloid leukemias are characterised by mutation and altered expression of a range of tyrosine kinases. Over 90% of chronic myeloid leukemias (CML) harbour the Philadelphia chromosome, resulting in expression of the BCR/ABL fusion protein, a constitutively active tyrosine kinase that is essential for survival of the CML cells. Acute myeloid leukemia (AML) is a heterogeneous disease characterised...